Description

PT-141 — Melanocortin Peptide Nasal Spray for Neuroendocrine Research

PT-141 (Bremelanotide) is a synthetic melanocortin peptide developed for laboratory and scientific research applications. In academic and preclinical literature, PT-141 is widely examined for its interaction with central melanocortin receptor pathways involved in neuroendocrine signaling and behavioral response models.

This intranasal spray formulation is designed to support research into peptide stability, nasal delivery dynamics, and central nervous system pathway engagement, providing a consistent and controlled format for analytical and experimental investigation.

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Research Areas of Interest

✅ Melanocortin Receptor Pathway Studies – PT-141 is investigated for its activity at melanocortin receptors (MC3R, MC4R) in laboratory models.

✅ Neuroendocrine Signaling Research – Studied in experimental settings related to hypothalamic signaling and neurochemical regulation.

✅ Behavioral & Motivational Pathway Models – Evaluated in preclinical research exploring centrally mediated behavioral response markers.

✅ Neurotransmitter Interaction Analysis – Examined for indirect interactions with dopamine-related signaling pathways in controlled research environments.

✅ Intranasal Delivery & Absorption Research – The nasal spray format supports investigation into peptide transport, absorption modeling, and formulation stability.

All references apply strictly to laboratory and preclinical research contexts.

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Scientific Overview

PT-141 is a synthetic cyclic peptide derived from α-MSH (alpha-melanocyte-stimulating hormone), engineered to selectively engage melanocortin receptors while demonstrating improved stability compared to earlier peptide analogs. In research literature, PT-141 is frequently used to study centrally mediated neuroendocrine signaling independent of peripheral vascular mechanisms.

Its structure and receptor specificity make PT-141 a valuable tool in experimental models focused on central signaling pathways, peptide transport, and neurochemical modulation.

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Mechanism of Action (Research Context)

Melanocortin Receptor Activation:

PT-141 is studied for its selective interaction with MC3 and MC4 receptors in central nervous system models.

Neuroendocrine Pathway Evaluation:

Investigated for its role in hypothalamic signaling and centrally regulated neurochemical cascades.

Behavioral Signaling Models:

Used in laboratory research examining motivation-linked and reward-associated neural pathways.

Peptide Stability & Nasal Transport:

The intranasal formulation supports research into peptide integrity, absorption efficiency, and CNS delivery modeling.

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Quality, Formulation & Packaging

Purity: Verified via analytical methods such as HPLC/MS

Form: Nasal spray solution designed for research convenience

Production: Small-batch formulation under controlled laboratory conditions

Packaging: Sealed units for stability, consistency, and traceability

Fulfillment: Ships from a U.S.-based, climate-controlled facility with tracked delivery

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Usage & Research Compliance

PT-141 nasal spray is supplied strictly for laboratory research and analytical use.

• Not intended for human or animal consumption

• Not a drug, supplement, or therapeutic product

• No medical, neurological, or performance claims are made or implied

This product is intended solely for qualified research environments where proper handling, storage, and regulatory compliance are observed.